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Sadia Malik , MD

Research Overview

Dr. Malik has extensive clinical experience in pediatric cardiology and post-doctoral training in epidemiology. At the Arkansas Center for Birth Defects Research and Prevention at ACHRI, Dr. Malik reviews all cases with cardiac anomalies for accurate classification and coding for the National Birth Defects Prevention Study (NBDPS). She also leads studies on the epidemiology of congenital heart defects. These studies include the efficacy of antioxidant support in children with Down syndrome undergoing cardiac surgery, central pulse pressure as a predictor of aortic root dilation in Marfan syndrome, and maternal tobacco exposure, maternal hair cotinine levels during pregnancy, and the risk of cardiovascular malformations.

Malik S, Lemler M, Ramaciotti C. Trisomy 21 and early echocardiography: Evaluation of Guidelines. J J Clin Pediatr. 2005;44:39-42.

Hobbs CA, Cleves MA, Keith C, Malik S, James SJ. NKX2.5 and congenital heart defects: A population based study. Am J Med Genet. 2005:134:223-225.

Malik S, Caughy M, Schecter A, Fixler DE. Proximity to hazardous waste sites and risk of congenital heart disease. Arch Environ Health, 2004; 59:177-181.

Hobbs CA, Malik S, Zhao W, James SJ, Melnyk S, Cleves MA. Maternal homocysteine and congenital heart defects. J Am Coll Cardiol. 2006 Feb 7; 47(3):683-5. Epub 2006 Jan 18.

Malik S, Cleves MA; Zhao W, Correa A, Hobbs CA. National Birth Defects Prevention Study. Association between congenital heart defects and small for gestational age. Pediatrics Electronic Pages Accepted. 2006.

To find publications additional publications by this author, please visit Pubmed Central, a National Institutes of Health-operated site for electronic distribution of life sciences research reports.

Research Support

American Heart Association

National Institutes of Health

Arkansas Biosciences Institute


Arkansas Center for Birth Defects Research and Prevention
13 Children's Way, Mail Slot 512-40
Little Rock, Arkansas 72204
1-877-662-4567 toll free