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Stephen Erickson, PhD
S. Erickson


Research Overview

Dr. Erickson serves as statistical geneticist in ACHRI's Center for Birth Defects Research and Prevention and is assistant professor in the UAMS Departments of Pediatrics and Biostatistics.  He is currently investigating the genetic and environmental factors influencing congenital heart defects and other birth defects.

Dr. Erickson received his doctorate in statistics from UCLA and, in the spring of 2009, completed a postdoctoral fellowship with the Section on Statistical Genetics in the Department of Biostatistics of the University of Alabama at Birmingham (UAB).  He has extensive experience in the analysis of genomic microarrays, including the inference of DNA copy number variation (CNV) from genotyping array data.  Dr. Erickson's methodological research focuses on empirical and hierarchical Bayes models.


Key Publications

Erickson SW, Kim K, Allison DB.  Composite Hypothesis Testing:  An Approach Built on Intersection-Union Tests and Bayesian Posterior Probabilities.  Book chapter in Meta-analysis and Combining Information in Genetics and Genomics.  Chapman & Hall 2009.

Erickson SW.  A likelihood-ratio test of twin zygosity using molecular genetic markers.  Twin Res Hum Genet. 2008 Feb; 11(1):41-3.

Wineinger N, Kennedy RE, Erickson SW, Wojcynski MK, Bruder CE, Tiwari HK.  Statistical Issues in the Analysis of DNA Copy Number Variations.  Int J Comp Biol Drug Design. 2008; 1(4):368-395

Bruder CE, Piotrowski A, Gijsbers AA, Andersson R, Erickson SW, de Stahl TD, Menzel U, Sandgren J, von Tell D, Poplawski A, Crowley M, Crasto C, Partride EC, Tiwari H, Allison DB, Komorowski J, van Ommen GJ, Boomsma DI, Pedersen NL, den Dunnen JT, Wirdefeldt K, Dumanski JP.  Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles.  Am J Hum Genet. 2008 Mar;82(3):763-71. 

Erickson SW, Sabatti C.  Empirical Bayes estimation of  a sparse vector of gene expression changes.  Stat Appl Genet Mol Biol. 2005; 4:Article22.

Research Support

Principal Investigator:  Genome-Wide Association Test of DNA Copy Number Variation in Congenital Heart Defects.  Arkansas Children's Hospital Research Institute CUMG.

Arkansas Center for Birth Defects Research and Prevention
13 Children's Way, Mail Slot 512-40
Little Rock, Arkansas 72204
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